Tools
ACHEMA 2012ACHEMA 2012

Pharmaceuticals

Integrated Laboratory Solutions – Booth position 4

Laboratories are highly complex working environments with strict guidelines and regulations. The challenges in laboratories are to keep people, assets and the environment safe and secure, optimize operation, prevent cross-contamination and ensure regulatory compliance.

An essential piece of safety equipment in labs is the fume hood, which provides lab users with a well protected zone for conducting tests and experiments. Selective air flow or extraction prevents the formation of contaminated air or explosive concentrations as well as uncontrolled reflow back into the room. Complete integration into the building management system fully adapts the primary installations to the laboratory’s needs. The ability to dynamically adjust air exchange rates, volumetric flows and duct pressures improves energy efficiency by as much as 50% over constant regulation.

As a reliable and experienced solution supplier, Siemens provides a full range of laboratory solutions from a single source: from fume hood control and monitoring, dynamic room regulation and adapted control and regulation of primary installations, access control, intrusion detection, intelligent video surveillance, fire detection, alarming and evacuation to complete integration into a management system. This results in maximized energy efficiency, minimized risks and increased safety - all while complying with regulatory requirements.


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Ultrapure Water - Booth position 2

Since 1984 Siemens develop, produce and sell ultra pure water systems, reverse osmosis equipment, electro-deionization systems from our facility in Barsbüttel close to Hamburg.

The experience Siemens has gained in over 30 years in the industry makes us an indispensable partner when it comes to turning drinking water into pure and ultra pure water.

Reliability, quality and customer contact are important to us, which is why you will find our network of after-sales service distributed across Germany and our offices and representatives in many other countries.


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Continuous Manufacturing - Booth position 6A

With electronic PAT tools in place, companies have the basis for continuous quality verification and Continuous Manufacturing. Continuous Manufacturing offers a variety of benefits in the form of

  • significantly reduced inventory,

  • lower quality control costs,

  • reduced or even no waste product.

Continuous Manufacturing is applicable to both APIs and to secondary manufacturing. Continuous Manufacturing processes typically anticipate a fast return on investment and cost savings in the 10-20% range compared to batch manufacturing.Facilities are less costly to build and 100% of capacity is utilized when they are in operation. A major saving comes from not having to take batches to the laboratory for analysis which can shrink the time taken getting the product to the patient from hundreds of days to something in the order of less than ten days.


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SIPAT - Booth position 6B

SIPAT is Siemens’ PAT software solution that supports QbD implementation. The PAT software features functions such as

  • data collection,

  • data mining,

  • real-time prediction of quality parameters,

  • version management,

  • online visualization,

  • as well as reporting and analysis of historical data

The benefits are

  • a better process insight,

  • real-time product release,

  • manufacturing performance improvement,

  • quality consistency improvement,

  • enabling advanced process control

  • and regulatory compliancy using online quality control

In the new version a lot of new features and enhancements were implemented:

  • Improved integration possibilities, supporting the new OPC UA platform

  • New features for chemometrical integration

  • Improved data mining

  • Ready for the last generation of IT platforms

  • SIPAT Express offers an embeddable PAT data management solution for OEM’s


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Flexible Fermenter Control - Booth position 15

As a partner to the pharmaceutical industry with many years of experience, Siemens creates scalable and tailored automation solutions that meet your specific needs. Based on the standard products from the Siemens product portfolio, such as SIMATIC BATCH, we conceive ISA-S88-compatible solutions that allow for a modular equipment set-up.

Based on our concept of Totally Integrated Automation, we ensure that your plant runs efficiently and is seamlessly integrated into the entire production process. Key in this approach is the integration of individual package units into a plant-wide DCS, boosting efficiency and process transparency.

Because all your components use the same automation structure, they are fully compatible and scalable, and meet the highest standards of reliability and longevity. This leads to simplified engineering, reduced training/ maintenance costs and less downtime due to standard components and interfaces.

The flexible fermenter control is a prime example of an integrated SIMATIC PCS 7 approach. This fit for purpose solution combines the use of innovative single use bioreactors with the latest PCS 7 Advanced Process Library functionalities. This results in multi-purpose production capabilities with optimal control of the fermentation process for every single product.

The structured programming and routing possibilities enable plant flexibility, maintaining a unified and transparent user interface.

Benefits of the Siemens’ flexible fermenter control concept:

  • Low level integration of package units using standard products from the SIMATIC family

  • Increased flexibility, allowing multi-purpose production

  • Higher operating efficiency: single HMI for the entire plant


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Drug Manufacturing. Totally Integrated Automation - Booth position 40

With the new Engineering Framework TIA Portal WinCC V11 the Control and Monitoring of drug manufacturing becomes easier: One Engineering Software from Basic Panel up to SCADA level by means of re-usage objects and standard libraries.

Siemens presents a solution for Drug Manufacturing Automation, run with TIA Portal WinCC V11 combined with the WinCC Premium Add-on Process Management.

The Monitoring and Control of production in filling line machines shown is based on the OMAC standard model and executed in a batch enabled SCADA System.

The Batch system allows the definition and planning of recipes, batch dispatching, electronic signatures, audit trails, manual batch record data entries, and automatically printed batch reports.


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Serialization - Booth position 31

With its global presence Siemens is the right partner to understand the different requirements of different sites, regulators and markets.

The Siemens comprehensive serialization solution uses open communication standards and offers the choice of a “retrofit” solution whereby serialization becomes integrated into the line or a “stand-alone”, modular installation. It enables supply chain security with contract manufacturers and distribution centers and outwards to the point of sale or point of use in pharmacy and health care settings. The Siemens technology reaches upwards into management and control systems, offering the functionality to track and trace along the supply chain.

Benefits of the Siemens serialization solution are:

  • modular and flexible architecture,

  • standard components,

  • comprehensive solution covering all levels, and

  • global reach.


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Optimized Production Line - Booth position 30

Boost your line efficiency with Optimized Packaging Line by applying our efficient operating and visualization concepts. Use our tested line architectures and software libraries to simplify machine integration. They are based on international standards, such as ISA and OMAC. Protect your investment by using selected products with long term availability and on-board diagnostics. Fewer hardware and software variants help to minimize your maintenance, support and spare part costs. Optimized Packaging Line also enables you to identify, evaluate and minimize your energy consumption plant wide. Cut your energy costs by up to 40% by using our energy efficient drives together with new gears or direct drive solutions. Reducing time to market is a key requirement of machine manufacturers. To meet this need, the Optimized Packaging Line Software Toolbox provides software libraries for packaging machine equipment modules in accordance to the ISA S88 standard. These equipment modules in combination with our SIMOTION Easy Project generator enable you to generate application software for modular machines in an automatic and consistent way. You can easily administer software variants, build your own libraries and greatly improve your engineering efficiency. We provide you with all the reliable system components you need to build your own efficient packaging solution, from a powerful motion controller to the operator interface.

Packaging machinery manufacturers around the globe trust in Siemens’ worldwide presence and benefit from using our automation and drives solutions. We enjoy the cooperation with each customer and thank all of them for their trust.


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Best-in-class products for the pharmaceutical industry - Booth position 14

Increase your process efficiency with the comprehensive process instrumentation portfolio for the pharmaceutical industry including a wide range of process connections for hygienic requirements.


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SIMATIC IT – Manufacturing Execution and Intelligence - Booth position 18

SIMATIC IT for Life Sciences bridges the gap between the lab and the shop floor by integrating and optimizing development, quality and manufacturing processes.

  • Optimized manufacturing processes, integrated quality, shorter time-to-production and time-to-market

  • An MBR driven platform that optimizes all Life Sciences processes

  • Consistent weighing & dispensing of all material types, based on recipe specification and accurate data collection

SIMATIC IT for Process Industries has a scalable and modular approach that provides process industries with complete and real time equipment visibility and production line monitoring.

  • Automated real-time data collection for optimized asset management, reduced downtime and improved yield

  • Increased visibility for better decision support and continuous performance improvement

  • Scalable and modular approach


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